E: Package 'python-wxgtk2.8' has no installation candidate

I'm having trouble installing sudo apt-get install python-wxgtk2.8 python-wxtools wx2.8-i18n libwxgtk2.8-dev at Pi4.It failed with:

Reading package lists... Done
Building dependency tree
Reading state information... Done
Package python-wxgtk2.8 is not available, but is referred to by another package.
This may mean that the package is missing, has been obsoleted, oris only available from another source

Package libwxgtk2.8-dev is not available, but is referred to by another package.
This may mean that the package is missing, has been obsoleted, oris only available from another source

E: Package 'python-wxgtk2.8' has no installation candidate
E: Unable to locate package wx2.8-i18n
E: Couldn't find any package by glob 'wx2.8-i18n'
E: Couldn't find any package by regex 'wx2.8-i18n'
E: Package 'libwxgtk2.8-dev' has no installation candidate